Anti-PIASz (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

General description

PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway. PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes. PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes.

Immunogen

PIASZ (NP_113637, 79-115)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PIASz.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.